Potential of Hydrogels Based on Poly(Ethylene Glycol) and Sebacic Acid as Orthopedic Tissue Engineering Scaffolds

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Biodegradable and Photopolymerizable Hydrogels for Tissue Engineering Based on Poly(ethylene glycol) and Sebacic acid

Introduction Poly (ethylene glycol, PEG) based macromers have been widely used in tissue engineering applications as hydrogel type biomaterials, mainly due to their well known hydrophilicity and biocompatibility [1,2]. In addition, PEG based biodegradable hydrogels have been reported [3] and have drawn more attraction for tissue engineering scaffolds and/or drug delivery systems [4,5]. However,...

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The goal of this work was to utilize the naturally derived bioactive polymer hyaluronic acid (HA) to create a combination tissue engineering scaffold and protein delivery device. HA is a non-immunogenic, non-adhesive glycosaminoglycan that plays significant roles in several cellular processes, including angiogenesis and the regulation of inflammation. In previous work, we created photopolymeriz...

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Development of Hydrogels and Biomimetic Regulators as Tissue Engineering Scaffolds

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ژورنال

عنوان ژورنال: Tissue Engineering Part A

سال: 2009

ISSN: 1937-3341,1937-335X

DOI: 10.1089/ten.tea.2008.0326